Medlea
LeaRes · predictive digital twin

The patient’s anatomy,
as a working model.

LeaRes turns CT and MRI into patient-specific functional twins: lungs, heart and vessels reconstructed, ventilation and flow simulated, in the browser, on your hospital’s GPU.

  • Lungs, heart and vessels
  • Agentic segmentation
  • Virtual spirometry
  • Active Learning
Virtual spirometry · forced expirationDemo case
Both lungs reconstructed from a chest CT during a simulated forced expiration
FEV1
3.20 L
FVC
4.38 L
FEV1/FVC
72.9 %

All MedLea solutions are browser-accessible and comply with GDPR · HIPAA · SOC2 · EU AI Act.

  • GDPR
  • HIPAA
  • SOC2
  • EU AI Act

Longitudinal data hides correlations no reader can hold in mind at once. LeaRes derives the morphofunctional biomarkers, keeps them comparable from scan to scan, and leaves the judgement where it belongs.

01
Morphology and airways

Anatomy that breathes

Lobes, airway tree and vessels reconstructed from the CT by AI agents, then set in motion: airflow simulated in every airway, regional ventilation in every lobe, on the same anatomy you would take to the operating room.

  • Five lobes, trachea and bronchial tree, segmented case by case
  • Airflow speed along the tree, from a GPU flow solver
  • Pre- and post-surgical scenarios on one patient-specific model
Airflow in the airways and parenchyma
Anatomy that breathes
02
Reinflation and hyperdistension

Regional ventilation, slice by slice

The breathing twin yields regional biomechanics: where the lung inflates, where it over-distends, how the two lungs share the breath. Maps and AI-derived biomarkers you can read on the familiar MPR views, for ICU and surgical research.

  • Ventilation rate mapped onto axial, coronal and sagittal slices
  • Ventilated volume per lobe, FEV1 and FVC per lobe
  • Risk maps as research biomarkers, never as a verdict
Airflow and biomechanics of the airways and parenchymaDemo case
Regional ventilation, slice by slice
03
Blood flow and perfusion

The vessels, from the same scan

Pulmonary arteries and veins, heart and aorta reconstructed alongside the lungs. The geometry a flow study needs, ready for perfusion research in functional radiology.

  • Vascular tree and great vessels as separate, labelled structures
  • One coordinate frame with the airways and lobes
  • Exportable geometry for simulation and CAD
Heart, aorta, pulmonary arteries and veinsDemo case
The vessels, from the same scan

Engineering

From anatomy to CFD, in the same workstation

The engineering workspace takes the reconstructed anatomy, or an imported CAD geometry, sets materials and boundary conditions, and runs the flow. The full solver for the final answer; surrogates for the exploration.

  • 01

    Patient-specific CFD

    A lattice-Boltzmann multiphysics solver on GPU computes airflow, pressure and particle transport in the patient’s own airways and vessels.

  • 02

    CFD surrogates

    AI surrogates trained on full CFD runs return the same quantities in a fraction of the time, so settings and device variants can be explored interactively before the full solver confirms the final case.

  • 03

    Devices in real anatomy

    Catheters, stents, flow diverters and ventilator circuits placed in the reconstructed anatomy or imported as CAD, with inlets, outlets and materials set in the browser.

Device CFD · streamlines in a ventilator circuit
Device CFD · streamlines in a ventilator circuit
Set-up in LeaRes · materials, 35 inlets and outletsDemo case
Set-up in LeaRes · materials, 35 inlets and outlets

Active Learning

A model your department trains on its own cases

Name the pattern, annotate inside LeaRes, train on your GPU, correct what the model proposes. Each round leaves less to correct. The data never leaves the hospital.

How the platform works
  1. 01
    Define the pattern
  2. 02
    Annotate
  3. 03
    Train on your GPU
  4. 04
    Correct the proposal
AGENTIC WORKFLOW · FROM SCAN TO SIMULATION

LeaFlow

An agentic workflow that takes a scan through segmentation, reconstruction and simulation.

LeaFlow is Medlea's agentic workflow. AI agents carry a CT or MRI scan through segmentation, anatomical reconstruction and simulation set-up, step by step. At its core sits a multiphysics simulation engine: it models how blood, air, urine, drugs, contrast agents and particles move through the patient's anatomy, and how a medical device — catheter, implant, inhaler, stent — changes that flow. Device and tissue can move and deform together, so a clinician can rehearse a procedure and a device maker can test a prototype in a virtual patient before building it.

Applications
04

Respiratory

Aerosol therapy, nebulisers and smart inhalers: LeaFlow follows the particles through moving airways and shows where they deposit and how much of the dose is exhaled.

  • Endotracheal tubes and bronchial blockers: how they change airflow and regional stress.
  • Results that inform ventilation settings and the design of inhaled therapies.
Respiratory
05

Cardiovascular

Stents, grafts and valves: LeaFlow measures their effect on local flow, wall shear stress and downstream perfusion, inside the vessels of the individual patient.

  • Restenosis, thrombosis and embolisation risk, from anatomy, flow and particle transport together.
  • For pre-procedural planning and for virtual prototyping of new devices.
Cardiovascular
06

Renal and urological

Ureteral stents, catheters and artificial sphincters: LeaFlow shows how they change urinary flow, pressure gradients and the transport of sediments and particles.

  • Encrustation, reflux and partial obstruction, explored before they happen in a patient.
  • Prototypes tested in virtual anatomies, with fewer animal models and physical builds.
Renal and urological
07

Anatomical reconstruction

CT and MRI scans become accurate 3D models: airways, vessels, renal tracts and other flow-relevant anatomy are identified and reconstructed automatically, case by case.

  • Captures both the large structures and the fine detail a simulation depends on.
  • One model serves the simulation, the CAD export and the browser viewer.
Anatomical reconstruction
08

One workflow for clinicians and engineers

Patient models move in and out of standard CAD tools. Engineers place a stent, valve or catheter in real anatomy; surgeons review the same placement beforehand.

  • Export to CAD for geometric editing, structural analysis or 3D printing.
  • Imaging, simulation and design in one cycle, shared by clinical and engineering teams.
One workflow for clinicians and engineers
09

In the cloud or on premises, from the browser

LeaFlow runs in the cloud or on premises, on GPUs, for real-time or batch simulations, and every step is driven from an ordinary web browser.

  • An API connects it to surgical planning tools, training simulators and validation pipelines.
  • Velocity fields, deposition maps, pressure gradients and residence times, in a visual interface.