A General-Purpose Anatomical Flow Simulator
FlowLeap is Medlea’s next-generation simulation engine built to model and predict complex flow dynamics across a wide range of anatomical systems.
Unlike traditional simulators restricted to specific organs or flow types, FlowLeap is a modular, multiphysics simulation framework capable of representing airflow, blood flow, lymphatic flow, urinary excretion, and even the propagation of therapeutic aerosols or pathogens.
This versatility makes it a cornerstone technology for digital twin applications in medicine, where capturing the full physiological interplay is critical.
Cross-Domain Simulations with Integrated Device-Human Modeling
FlowLeap is engineered for advanced, cross-domain medical simulations that span multiple organ systems and physiological processes — but its true strength lies in its ability to also simulate the interaction between medical devices and the human body. This makes it a powerful tool not only for clinical understanding and decision support, but also for medtech innovation, prototyping, and regulatory validation. Whether it’s a catheter, implant, aerosol device, or robotic intervention, FlowLeap simulates how these systems behave within accurate, patient-specific environments under realistic physiological conditions.
What sets FlowLeap apart is its multiphysics foundation combined with support for dynamic, moving boundaries, allowing for accurate simulation of both fluid flow and mechanical deformation — key to understanding how devices and tissues co-evolve during use. Whether you’re a clinician preparing for an intervention or a developer designing the next generation implantable device, FlowLeap enables you to simulate, visualize, and optimize device-human interactions in silico, safely and with unmatched realism.
Case Studies
In respiratory care, FlowLeap enables simulations of aerosol-based drug delivery systems, nebulizers, and smart inhalers. It models how device-generated particles move through dynamic airway geometries, deposit in targeted regions, or are exhaled — accounting for flow rate, breathing cycle, airway resistance, and posture. It also allows the simulation of airway management devices such as endotracheal tubes or bronchial blockers, showing how they alter airflow patterns or increase regional stress, providing key data for ventilator setting optimization and airway protection strategies.
In the cardiovascular field, FlowLeap can simulate the implantation of stents, grafts, and valves, evaluating their effect on local flow dynamics, wall shear stress, and downstream perfusion. It can assess risks of restenosis, thrombosis, or embolization by combining patient-specific anatomy with flow physics and particle transport. The platform supports pre-procedural planning, as well as virtual prototyping of new cardiovascular devices under variable flow, pressure, and anatomical constraints.
In renal and urological systems, FlowLeap can simulate the placement of ureteral stents, catheters, or implants such as artificial sphincters. It models how these devices influence urinary dynamics, local pressure gradients, and the flow of particles or sediment. This capability extends to simulating scenarios like stent encrustation, reflux prevention, or the impact of partial obstruction. Device design teams can use FlowLeap to iteratively test prototypes in realistic virtual anatomy, reducing reliance on animal models and physical mockups.
Anatomical Reconstruction from Imaging
FlowLeap includes a powerful imaging pipeline that transforms tomographic datasets—such as CT and MRI scans—into high-resolution, anatomically accurate 3D models. Using AI-enhanced detection, the platform automatically identifies and reconstruct airways, vascular structures, renal tracts, and other flow-relevant anatomical domains. The resulting models retain detailed spatial fidelity, capturing both the macro-structure and fine-grained features critical for physiological simulations. This capability enables clinicians and researchers to simulate interventions based on patient’s anatomy, supporting personalized decision-making and predictive diagnostics.
CAD Integration
FlowLeap is fully integrated with industry-standard CAD platforms, enabling the import, modification, and export of custom geometries within anatomical contexts. Engineers and medtech designers can introduce medical devices—such as stents, valves, catheters, or delivery systems—into the patient-specific model and explore how their geometry affects local flow and tissue interaction. Conversely, anatomical models can be exported to CAD environments for advanced geometric manipulation, structural analysis or 3D printing.
A Unified Platform for Clinical and Engineering Collaboration
By combining automated reconstruction and CAD compatibility, FlowLeap facilitates a unified workflow across clinical and engineering teams. Surgeons can visualize proposed device placements in real anatomy; biomedical engineers can simulate dynamic mechanical responses under realistic physiological conditions. Whether the goal is to plan an intervention, validate a new device prototype, or assess performance under adverse scenarios, FlowLeap connects imaging, simulation, and design into a continuous, collaborative loop.
